“Ankaferd's anti-infective properties add a new value to its hemostatic effect in the healing of infected hemorrhagic wounds.”[1]

“The antimicrobial activity of ABS was investigated on 102 clinical isolates. ABS is significantly active against all investigated bacteria.”[2]

“The effectiveness of ABS solutions in achieving significant logarithmic reductions in foodborne pathogens of Helicobacter pylori has been observed. This study confirms that ABS has antibacterial (Anti-H. pylori) effects.”[3]

Plants are known to produce certain chemicals that are naturally toxic to bacteria. Many scientific studies have confirmed the antimicrobial activity of plant extracts, especially showing great potential against multidrug-resistant bacteria.

Thanks to the herbal content of Ankaferd Blood Stopper® (ABS), it is a strong and antibacterial, sterile and antifungal hemostatic agent. It destroys the microorganisms in and around the application area.

The herbaceous plants in ABS each have known effects on blood cells, endothelium, angiogenesis, cell proliferation and other physiological mediators [4].

• Thymus vulgaris has antioxidant properties and antimicrobial activity [5].
• Recent reports have shown that Glycyrrhiza glabra has antimicrobial, antioxidant, antifungal as well as anti-inflammatory effects [6].
• Alpinia officinarum has antioxidant and antimicrobial activity. [7]
• Vitis vinifera seed extract is associated with a wide spectrum of pharmacological effects, including antioxidant, anti-inflammatory and antimicrobial effects [8].
• Likewise, Urtica dioica has been reported to be an antimicrobial agent in the pharmaceutical and food industries [9].

References

[1] Akkoc M, Akcelik M, Haznedaroglu IC, Goker H, Turgut M, Aksu S, Kirazlı Ş, Fırat HC. In Vitro Anti-Bacterial Activities of Ankaferd Medicinal Plant Extract. Meeting Supplement of Int J Lab Hematol 2008;30:95.

[2] Fisgin NT, Cayci YT, Coban AY, Ozatli D, Tanyel E, Durupınar B. Tulek N. Antimicrobial activity of plant extract Ankaferd Blood Stopper. Fitoterapia 80 (2009) 48–50

[3] Ciftciler R, Koluman A, Haznedaroglu IC, Akar N. Effects of Ankaferd hemostat on Helicobacter pylori strains and antibiotic resistance. Turk J Med Sci (2019) 49: 347-355

[4] Kurt M, Onal IK, Akdogan M, Kekilli M, Arhan M, Sayilir A, Oztas E, Haznedaroglu IC. Ankaferd Blood Stopper for controlling gastrointestinal bleeding due to distinct benign lesions refractory to conventional antihemorrhagic measures. Canadian Journal of Gastroenterology and Hepatology 2010; 24: 380-384.

[5] Lee S-J, Umano K, Shibamoto T, Lee K-G. Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgaris L.) and their antioxidant properties. Food Chemistry. 2005;91:131-7.

[6] Dirican E, Turkez H. In vitro studies on protective effect of Glycyrrhiza glabra root extracts against cadmium-induced genetic and oxidative damage in human lymphocytes. Cytotechnology 2014; 66: 9-16.

[7] Srividya A, Dhanabal S, Misra V, Suja G. Antioxidant and antimicrobial activity of Alpinia officinarum. Indian Journal of Pharmaceutical Sciences. 2010; 72: 145.

[8] Nassiri‐Asl M, Hosseinzadeh H. Review of the pharmacological effects of Vitis vinifera (grape) and its bioactive constituents: an update. Phytotherapy Research 2016; 30: 1392-403.

[9] Modarresi-Chahardehi A, Ibrahim D, Fariza-Sulaiman S, Mousavi L. Screening antimicrobial activity of various extracts of Urtica dioica. Revista de Biologia Tropical 2012; 60: 1567- 1576.